FREQUENTLY ASKED QUESTIONS
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QBREXZA cloth is a topical prescription anticholinergic medicine used on the skin to treat excessive underarm sweating (primary axillary hyperhidrosis) in adults and children 9 years of age and older.
It is not known if QBREXZA is safe and effective in children under 9 years of age.
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The main active ingredient in QBREXZA, glycopyrronium, works by blocking the receptors that tell the body to make sweat, so your body makes less sweat. QBREXZA reduces the amount of sweat that is made at the source.
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Do not use QBREXZA if you have certain medical conditions that can be made worse by taking an anticholinergic medicine, such as glaucoma, severe ulcerative colitis, or certain other serious bowel problems associated with severe ulcerative colitis, myasthenia gravis, or Sjogren’s syndrome.
Talk to your healthcare provider if you are not sure if you have a medical condition that can be made worse by taking an anticholinergic medicine. Please ask your healthcare provider for more information.
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Before using QBREXZA, tell your healthcare provider about all of your medical conditions, including if you:
- Have prostate or bladder problems, or problems passing urine
- Have kidney problems
- Are pregnant or plan to become pregnant. It is not known if QBREXZA will harm your unborn baby.
- Are breastfeeding or plan to breastfeed. It is not known if QBREXZA passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment with QBREXZA.
Tell your healthcare provider about all the medicines you take, including prescription medicines, over-the-counter medicines, vitamins, and herbal supplements.
QBREXZA may affect the way other medicines work causing side effects. Especially tell your healthcare provider if you take anticholinergic medicines.
Know the medicines you take. Keep a list of your medicines with you and show it to your healthcare provider and pharmacist when you get a new medicine.
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QBREXZA can cause serious side effects, including:
- New or worsened urinary retention. People who use QBREXZA may develop new or worse urinary retention. Urinary retention can be caused by a blockage in your bladder. Urinary retention can also happen in men who have a larger than normal prostate. Symptoms of urinary retention may include:
- Difficulty urinating
- Urinating frequently
- Urination in a weak stream or drips
- Full bladder or difficulty emptying your bladder (distended bladder)
If you have these symptoms, stop using QBREXZA and call your healthcare provider right away.
- Problems with control of your body temperature. QBREXZA can cause you to have decreased sweating in areas other than the underarm area, which could cause you to become overheated and to develop heat illness. When in hot or very warm temperatures, watch for generalized lack of sweating and avoid use if you are not sweating in these situations. Symptoms of heat illness include:
- Hot, red skin
- Decreased alertness or passing out (unconsciousness)
- Fast, weak pulse
- Fast, shallow breathing
- Increased body temperature (fever)
Stop using QBREXZA and call your healthcare provider right away if you develop any of these symptoms.
- Blurred vision. Avoid touching eyes. If you develop blurred vision during treatment with QBREXZA, call your healthcare provider, stop using QBREXZA, and do not drive, operate machinery, or do hazardous work until your vision is clear.
The most common side effects of QBREXZA include:
- Dry mouth
- Dilation of the pupils of your eyes (mydriasis)
- Sore throat
- Skin redness, burning/stinging, or itching in underarm area
- Headache
- Problems with urination
- Blurred vision
- Nasal dryness
- Throat, eye, and skin dryness
- Constipation
These are not all of the possible side effects of QBREXZA. Call your healthcare provider for medical advice about side effects.
- New or worsened urinary retention. People who use QBREXZA may develop new or worse urinary retention. Urinary retention can be caused by a blockage in your bladder. Urinary retention can also happen in men who have a larger than normal prostate. Symptoms of urinary retention may include:
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The active ingredient in QBREXZA is glycopyrronium tosylate. The inactive ingredients are citric acid, dehydrated alcohol, purified water, and sodium citrate.
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Only your healthcare provider can tell you if QBREXZA is right for you. If you think you sweat more than normal under your arms, or if your underarm sweating is bothersome and/or interferes with daily activities, ask your healthcare provider about options for treating it, including QBREXZA.